Department of Veterinary Pharmacology and Toxicology, Jabalpur

Brief History :

Department of Materia Medica earlier, later Pharmacology and now known as Veterinary Pharmacology and Toxicology was established as an independent Department in 1965. The Post graduate degree programme (M.V.Sc.) was started in 1968 and Ph.D. in 1979. Till December 2017, 53 students have been awarded M.V.Sc and 11 Ph.D. degrees in the discipline of Veterinary Pharmacology and Toxicology. Government Veterinary College offered courses leading to degree of Veterinary Science (B.V.Sc.) and was affiliated to university of Sagar After the superannuation of Dr. K.S. Bhandari, Dr. Y.P. Sahni became the Head of the department. In the year 2007, four new Assistant Professors namely, Dr. Nitish Kumar, Dr. Neetu Rajput, Dr. Kshemankar Shrman and Dr. Vidhi Gautam joined the department. In the year 2010, Dr. R.K. Sharma was transferred from Veterinary College, Mhow to Veterinary College, Jabalpur and from January 2012 onwards, Dr. R.K Sharma is working as Head of the department. Presently along with Dr. R. K. Sharma, Dr. K. Shrman Dr. Vidhi Gautam and Dr. Sachin Jain are the faculty members in the department.

Objectives of the Department :

Provide quality education and updated technical information in the subject of Pharmacology & Toxicology at all academic levels.
Undertake basic, applied and need based research in pharmacology & Toxicology.
Promote effective interaction among faculty and students.
Develop effective and cost sustainable finger print profile of herbal remedies for animal health.

Education :

Undergraduate :-

S.NO.	Code of Course	Name of Course	Credit Hrs.
1.	VPT-311	General Pharmacology I	2+1
2.	VPT-321	General Pharmacology II	2+1

Postgraduate :-

S.NO.	Code of Course	Name of Course	Credit Hrs.	Semester
1.	VPT 501	Concepts of Pharmacology, Drug Design and Development*	2+0	I
2.	VPT 502	Autonomic and Autacoid Pharmacology*	2+1	I
3.	VPT 503	CNS Pharmacology	2+1	I
4.	VPT 504	Digestive and Respiratory Pharmacology	2+1	I
5.	VPT 505	Cardiovascular and Urinary System Pharmacology	2+0	I
6.	VPT 506	Endocrine and Reproductive Pharmacology	2+1	I
7.	VPT 507	Chemotherapy*	2+1	II
8.	VPT 508	Toxicology of Xenobiotics*	2+1	II
9.	VPT 509	Toxinology	2+1	II
10.	VPT 510	Pharmacological Techniques*	0+2	II
11.	VPT 511	Techniques in Toxicology*	0+2	II
12.	VPT 512	Ethnopharmacology	1+1	II
13.	VPT 513	Fundamentals of Pharmacokinetics	1+1	II
14.	VPT 591	Master’s Seminar*	1+0	I/II
15.	VPT 599	Master’s Research	30	I/II

*Core Course

Ph.D :-

S.NO.	Code of Course	Name of Course	Credit Hrs.	Semester
1.	CPE-RPE 600	Research and Publication Ethics #	2+0	I
2.	VPT 601	Molecular Pharmacology*	3+0	I
3.	VPT 602	Advances in Autacoid Pharmacology	1+0	I
4.	VPT 603	Pharmacology of Herbal Drugs	2+1	I
5.	VPT 604	Biotransformation of Xenobiotics	2+0	I
6.	VPT 605	Clinical Pharmacology and Pharmacokinetics*	2+1	I
7.	VPT 606	Pharmacogenomics	2+0	I
8.	VPT 607	Immunopharmacology and Immunotoxicology	2+0	II
9.	VPT 608	Molecular Toxicology	3+0	II
10.	VPT 609	Clinical Toxicology*	2+1	II
11.	VPT 610	Ecotoxicology	3+0	II
12.	VPT 611	Regulatory Toxicology	2+1	II
13.	VPT 690	Special Problem	0+1	II
14.	VPT 691	Doctoral Seminar I*	1+0	I/II
15.	VPT 692	Doctoral Seminar II*	1+0	I/II
16.	VPT 699	Doctoral Research	75	I/II

*Core Course

Research :

Salient Achievements :

Studies on prevalence, Characterization and inhibitory potential of herbs on extended spectrum beta Lactamase Escherichia Coli in Broilers

Research Scholar : Dr. Arpita Shrivastav (2016) Ph.D

Major advisor : Dr. R. K. Sharma

Antibiotic resistance due to ESBL E. coli was prevalent in healthy broilers of Jabalpur with a prevalence per cent of 33.5. Clove oil showed maximum and Tulsi leaves showed minimum inhibitory potential and per cent inhibition ESBL enzymes, combination of Clove oil, Tulsi and Pomegranate produced better activity than individual herbs.

Studies on antibacterial activity of endophytic bacteria isolated from Neem, Mulberry and Aloe Vera leaves

Research Scholar : Ankit Kumar Singh (2016)

Major advisor : Dr. R. K. Sharma

Endophytic bacteria were present in leaves of Azadiracta indica (neem), Morus nigra (mulberry) and Aloe barbadensis (aloe vera) leaves. Endophytic bacteria from neem possess maximum antibacterial activity against Staphylococcus aureus, Streptococcus pyogens, Escherichia coli, Salmonella Typimurium and Klebsiella pneumonia. Endophytic bacteria from mulberry possess antibacterial activity against Streptococcus pyogens. Endophytic bacteria form Aloe vera possess antibacterial activity against Staphylococcus aureus and Klebsiella pnemoniae. Endophytic bacteria from neem showed probiotic like activity.

Completed Research Projects :

Studies on anti-inflammatory, antibacterial and immuno modulatory activity of Noni (Morinda citrifolia) in experimental animals
Evaluation of Antibacterial and Immunomodulatory activity of cow urine with wheat grass and aloe-vera in poultry

Ongoing Research Projects :

All India Outreach Programme on "Drug Residues and Environmental Pollutants"
All India Outreach Programme on "Ethno Veterinary Medicine"

Extension Education :

Training camp for villagers are organized for creating awareness about the toxic residues of chemicals.
Pamphlet, leaflet and extension pocket books developed.
Radio talk delivered by faculty members on various topic of interest of farmers.

Publications :

Kewat RR, Sharma RK, Gautam Vidhi and Soman Swathi (2019). In vitro antibacterial activity of endophytic bacteria isolated from Moringa Olefera Leaves. Journal of Veterinary Pharmacology & Toxicology.Vol.18/P-60-65
Sharma Neha, Singh, Randhir, Jawre, Shobha, Vaish, Rakhi and Sharma, R.K. (2019). Comparison of wound healing properties of herbal ointments with povidone iodine on basis of histological changes. Journal of Animal Research, v. 9 (1): 173-177.
Mishra Prateek, Gautam Vidhi, Sharma R.K., Tiwari Anushri and Sawarkar Alka (2020). Microneedle: A useful tool for drug delivery system. Journal of Pharmacology and Phytochemistry. P-340-344.
Jain Anand kumar, Mishra Aditya, Singh A.P, Baghel RPS, Sharma R.K, and Shukla S.N. (2020). Comparative effects of inorganic and organic trace minerals (Zn, Se and Cr) supplementation on expression of ChTLR2b gene in broilers. International Journal of Chemical studies. P-2866-2870.
Jain Anand Kumar, Mishra Aditya, Craesar D Deepika, Shakkarpude Jyotsana, Mourya Arun, Baghel RPS and Sharma R.K. (2020). Can different concentration of chelated and inorganic trace minerals (Zn, Se and Cr) be an effective supplement for better production performance and carcass traits in broilers?. Journal of Entomology and Zoology studies. P.197-204.
Mourya, Arun, Shulkla, P.C. Gupta, D. K. Sharma, R. K., Nayak, Anju, Singh, Brijesh, Jain, Anand and Pradhan, Shashi (2020). Prevalance of subclinical mastitis in cows in and around Jabalpur, Madhya Pradesh, Journal of Entomology and Zoology Studies, 8 (4): 40-44.
Mourya, Arun, Shulkla, P.C. Gupta, D. K. Sharma, R.K., Nayak, Anju, Singh, Brijesh, Kabita Roy, Biswajit Roy, Anand Jain and Shashi Pradhan (2020). Comparative efficacy of dry cow therapy and internal teat sealant on intramammary infection during subsequent lactation. International Journal of Chemical studies. P.14-17.
Shukla Sanjay, Nayak A., Sharma R.K., Shukla P.C. and Singh R.V. (2020). Evaluation of in vitro antibacterial activity of phage lysate against microbial pathogen isolated from septic wounds. Int. j. curr. Microbiol. App. Sci.9(10):1214-1217.
Singh Brejesh, Shukla Chandra Pramod, Sharma Rajesh Kumar, Mourya Arun, Singh Ranvijay and Jadav Kajal (2020). Prevalence, risk factors and current antibiogram assay associated with subclinical Escherichia coli mastitis in goats. International Journal of Livestock research, vol.10(11):P-146-149.
Dubey (Upadhyay)Shagun, Ahmad Yusra, Sharma Rajesh Kumar and Kohli Seema(2020). Huperzinea: Pharmacological and Therapeutic Potential. Pharmacognosy Communications, vol. 10(4), 2020.
Dubey (Upadhyay) S, Ahmad Y, Kohli S, Sharma RK.(2021). Neuroprotective effect of Galantamine against experimentally induced oxidative stress in IMR 32 cells. International Journal of Biology, Pharmacy and Allied Science (IJBPAS) vol. 10(7):X-X.
Sawarkar Alka, Sharma R.K., Gautam Vidhi, Shrman K and Jain Sachin(2021). Enzymatic activity of endophytic bacteria from Tamarindus indiaca leaves. Journal of The Pharma Innovation 2021; 10(1): 249-254. Rating 5.02.
Singh Prakash, Shrman K, Sharma R. K., Meena N. S., Kumar Nitesh and Kishor Kamal(2021). Saftey assessment of piperine after oral administration in sirohi goats. Journal of Entomology and Zoology Studies; 9(1): 753-755

Facilities Available :

Smart television with audio system
Undergraduate laboratory
Post graduate laboratory
Departmental library
Research instruments

Herbal Zone

Herbal Garden

ATOMIC ABSORPTION SPECTROPHOTOMETRY

LIQUID CHROMATOGRAPHY MASS SPECTROMETRY

Thrust Areas of Research :

Indigenous Pharmacology
Analytical studies
Residual studies
Detection of toxicants and drug residues
Standardization of bioactive constituents of Ethno-Veterinary Medicine

Services Offered :

Trainings

Module No.	Module Details	Stake Holders	Minimum Qualification	Minimum Duration Of Training	Number Of Candidates Acceptance	Frequency Of Training In One FY	Fee Structure For Various Categories (Rs.)
1.	Training in laboratory animal care and management	Sponsored students	12th pass with biology subject	7 days	Category -I 5-10 candidates in a batch	Biannual	2000/- per trainee
2.	Training in laboratory animal care and management	Sponsored students	12th pass with biology subject	7 days	Category –II individual sponsored candidate	As per requirement of sponsorers	5000/-per trainee
3.	Basic training in Pharmacology	Sponsored students	Graduate in life sciences	3 month	5-10 candidates in a batch	Biannual	10000/- per trainee
4.	Basic training in chemotherapy and toxicology	Sponsored students	Graduate in life sciences	3 month	Category -I 5-10 candidates in a batch	Biannual	10000/- per trainee
5.	Diploma in laboratory animal care and management	Sponsored students	12th pass with biology subject		20 candidates in a batch	Annual	20000/- per trainee

Pharmacy Preparation :

Pharmacy preparations
Gastric sedative powder
Sulphur ointment
Zinc oxide ointment
Iodine ointment
PP lotion
Golden lotion
Lugol’s iodine

Faculty :

S.NO.	Name	Designation	Qualification
1.	Dr. R.K. Sharma	Professor & Head	Ph.D.
2.	Dr. K. Shrman	Associate Professor	Ph.D.
3.	Dr. Vidhi Gautam	Associate Professor	Ph.D.
4.	Dr. Syamantak Mani Tripathi	Associate Professor	Ph.D.
5.	Dr. Sachin Jain	Assistant Professor	Ph.D.